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KMID : 1103920090150030362
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Korean Journal of Hepatology
2009 Volume.15 No. 3 p.362 ~ p.369
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Four patients with hepatitis A presenting with fulminant hepatitis and acute renal failure and who underwent liver transplantation
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Oh Se-Hoon
Lee Joon-Hyoek
Hwang Ji-Won
Kim Hye-Young
Lee Chang-Hoon
Gwak Geum-Youn
Choi Moon-Seok
Koh Kwang-Cheol
Paik Seung-Woon
Yoo Byung-Chul
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Abstract
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Hepatitis A is generally known as a mild, self-limiting disease of the liver, but in rare instances it can progress to fulminant hepatitis, which may require liver transplantation for recovery. Such cases are known to be related to old age and underlying liver disease. We report four cases of hepatitis A in which patients presented with fulminant hepatitis and acute renal failure and underwent liver transplantation. The following common features were observed in our cases: (1) occurrence in relatively old age (≥39 years old), (2) association with acute renal failure, (3) presence of hepatomegaly, and (4) microscopic features of submassive hepatic necrosis.
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KEYWORD
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Hepatitis A, Fulminant hepatitis, Acute renal failure, Liver transplantation
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